Wounds, if not properly managed, become one of the leading causes of morbidity and mortality in the country. That being said, the use of herbal drugs to explicate their potential in wound management and as natural remedies is growing due to their cheaper price and greater accessibility. Vernonia cinerea, also known as Tagulinaw, is a potential medicinal plant. The study aims to determine the antibacterial effect of Vernonia cinerea root extract against Staphylococcus aureus-induced wounds in mice. Vernonia cinerea dried roots were pulverized and the extract was made into an ointment. The study lasted for 16 days and applications of Mupirocin (positive control), Paraffin base (negative control), and Vernonia cinerea ointment was done once a day. The percent wound reduction in size was measured using a ruler and bacterial colony count was done. Results revealed that the Mupirocin and Vernonia cinerea ointment were comparable in eradicating Staphylococcus aureus on the wound of the mice based on the colony count done between the groups. On the other hand, the percent of wound reduction in size increases from the first day (4th) of measurement till the last day (16th) of observation. It was concluded that Vernonia cinerea ointment was effective in healing wounds and in the prevention of bacterial infections.
ISSN 2719-1990 (Print)
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