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Home⇛NRCP Research Journal⇛vol. 24 no. 2 (2025)

Ticks’ Antioxidant Complex and its Implications in Acaricide Resistance

Job A. Corcuera | Emmanuel P. Hernandez | Ian Cary B. Prado | Tetsuya Tanaka | Remil L. Galay

Discipline: others in veterinary sciences

 

Abstract:

Ticks are parasitic arthropods that feed on the blood of humans and animals, making them notorious for the transmission of numerous diseases. To survive their potentially toxic blood-feeding lifestyle, ticks have developed a complex antioxidant response mechanism to counteract oxidative stress. While several antioxidants have been identified in ticks, only a few have been fully studied in terms of their functions. Chemical acaricides have traditionally been used and remain to be widely utilized in the control of ticks. However, the emergence of tick resistance to these acaricides has become a global concern, leading to economic losses, decreased animal productivity, and the spread of tick-borne diseases. This review article discusses the physiological functions of tick antioxidants and their role in detoxification, focusing on how they are involved in acaricide resistance.



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